Essential Concepts in Clinical Research, 2nd Edition
This practical guide speaks to two audiences: those who read and those who conduct research. Clinicians are medical detectives by training. For each patient, they assemble clinical clues to establish causes of signs and symptoms. The task involves both clinical acumen and knowledge of medical research. This book helps guide clinicians through this detective work, by enabling them to make sense of research and to review medical literature critically. It will also be invaluable to researchers who conduct clinical research, particularly randomized controlled trials.
Building on previously published, peer-reviewed articles from The Lancet, this handbook is essential for busy clinicians and active researchers interested in research methods.
！洋書籍は不課税のため消費税不適用、電子書籍は消費税がご注文決済前に表示・適用されます！
！洋書籍は不課税のため消費税不適用、電子書籍は消費税がご注文決済前に表示・適用されます！
This practical guide speaks to two audiences: those who read and those who conduct research. Clinicians are medical detectives by training. For each patient, they assemble clinical clues to establish causes of signs and symptoms. The task involves both clinical acumen and knowledge of medical research. This book helps guide clinicians through this detective work, by enabling them to make sense of research and to review medical literature critically. It will also be invaluable to researchers who conduct clinical research, particularly randomized controlled trials.
Building on previously published, peer-reviewed articles from The Lancet, this handbook is essential for busy clinicians and active researchers interested in research methods.
この版の特長
For this Second Edition, the authors have revised and updated the original 16 chapters and added six new chapters. For busy clinicians and active researchers interested in research methods, this book provides helpful tools to derive satisfaction - indeed, fun - from clinical science.
特長
- Written by leaders in the field of clinical research who have published extensively with authorship of hundreds of articles in medical journals.
- The authorship includes one of the three authors of the CONSORT guidelines for the reporting of randomized controlled trials.
- The book presents the essential concepts to a wide array of topics including randomized control trials, descriptive studies, cohort studies, case-control studies, bias, and screening tests.
- The book utilises a readable and humorous prose style, lightening what can be a difficult area for clinical readers.
- Derived from decades of teaching clinical research in seminar settings the book will empower clinicians to make sense of, and critically appraise, current medical research and will enable researchers to enrich the quality of their work.
著者情報
| ISBN Number | 9780702073946 |
|---|---|
| Description Author List | By Kenneth Schulz, PhD, MBA, Distinguished Scientist, FHI360, Durham, North Carolina, USA; Clinical Professor, Department of Obstetrics & Gynecology, University of North Carolina School of Medicine, Chapel Hill, NC, USA and David A. Grimes, MD, Clinical Professor, Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill, NC, USA |
| Copyright Year | 2019 |
| Edition Number | 2 |
| Format | Book |
| Trim | 152w x 229h (6.00" x 9.00") |
| Imprint | Elsevier |
| Page Count | 262 |
| Publication Date | 3 Oct 2018 |
| Stock Status | IN STOCK |
eBooks : Built for busy schedules & tailored for your goals.
Affordable knowledge, built for you
Get the resources you need-often at a lower cost than print. Quality content designed to support your goals, without stretching your budget.
Seamless access wherever you are
Always in sync
Tools the make learning stick
Your eBook is ready whenever you are!
1. Check your email for your access code.
2. Sign into or create your VitalSource account and redeem your code.
3. Open your eBook - ready whenever you are!
FAQ
The access code for your new eBook will be sent in your order confirmation email. Your code can also be accessed in your My Account section on the Elsevier webshop. If you do not receive your code within a few minutes, please check your spam folder.
Step-by-step guidance on how to download Bookshelf and also redeem your code can be found here.
The access code for your new eBook does not expire. However, we always suggest redeeming immediately after purchase to start experiencing the benefits of and insights from your purchase. Important to note - the code provided is a single use code and only valid for the edition you purchase. It does not provide access to past nor future editions of the title.
You will have unlimited access to your eBook on the device to which it was downloaded.
Discover the various learning features that our eBooks offer on the Bookshelf® Reader! For example, you can highlight different text passages, create notes and flashcards, have the text read to you, etc. Particularly practical: You can also use your eBooks offline. More information on the learning functions can be found on the Vitalsource page.
Quality is our top priority. That's why we collaborate with the leading eBook reader provider VitalSource. VitalSource has its own eBook reader Bookshelf®, which you can easily download. This reader is very user-friendly and offers more features than other standard readers. For example, you can highlight different text passages, create notes and flashcards, have the text read to you, etc. Particularly practical: You can also use your eBooks offline. More information can be found on the Vitalsource page.
Elsevier offers its eBooks in ePub format, as we believe this format is best suited to display our content ideally on as many devices as possible.
You can return your eBook within 13 days of purchase. eBooks that have been partially printed or flipped through more than 15% are excluded from returns.
Any questions ?
Top Picks from Our Community
電子書籍
電子書籍
Karen Kenyon
Dec 2025
電子書籍
Edited by Joseph S. Kass
Dec 2025
電子書籍
Mary Alice Statkiewicz Sherer
Dec 2025
電子書籍
Edited by Jason Kolfenbach
Dec 2025
電子書籍
Edited by Michael O'Brien
Apr 2022
電子書籍
Elsevier
Dec 2025
電子書籍
Mary Alice Statkiewicz Sherer
Dec 2025
電子書籍
Monica Breedlove
Dec 2025
電子書籍
Matthew Buckland
Dec 2025
電子書籍
電子書籍
Margaret J. Fehrenbach
Dec 2025
電子書籍
電子書籍
電子書籍
Edited by Ragavendra R. Baliga
Nov 2025
電子書籍
Linda Anne Silvestri
Nov 2025
電子書籍
Elsevier
Nov 2025
電子書籍
Elsevier Inc and Jackie Koesterman
Jan 2025
電子書籍
Edited by Valeria Cohran
Nov 2025
Introduction
1. An overview of clinical research: the lay of the land
Observational studies
2. Descriptive studies: what they can and cannot do
3. Bias and causal associations in observational research
4. Cohort studies: marching towards outcomes
5. Case-control studies: research in reverse
6. Finding controls for case-control studies: compared to what?
7. Limitations of observational epidemiology
Screening tests
8. Uses and abuses of screening tests
9. Refining clinical diagnosis with likelihood ratios
Randomized controlled trials
10. Boosting participant recruitment in trials
11. Sample size calculations in randomized trials: mandatory and mystical
12. Generation of allocation sequences in randomized trials: chance not choice
13. Generation of allocation sequences in non-double-blinded randomized trials: guarding against guessing
14. Allocation concealment in randomized trials: defending against deciphering
15. Exclusions and losses in randomized trials: sample size slippages
16. Blinding in randomized trials: hiding who got what
17. Implementing treatment blinding in randomized trials
18. Surrogate endpoints and composite outcomes: shortcuts to unknown destinations
19. Multiplicity in randomized trials I: endpoints and treatments
20. Multiplicity in randomized trials II: subgroup and interim analyses
21. Conducting randomized trials as part of a prospective meta-analysis
Publishing
22. Reporting studies in medical journals: CONSORT and other guidelines
When you read that the authors of a book were proud to have "escaped the 1970s without owning a leisure suit," you just know it’s going to be good. Clearly, such authors have a different point of view—and a great sense of humor. Essential Concepts in Clinical Research is an accurate title; the book is a pragmatic guide to understanding and evaluating clinical research, and it is excellent. It is easy to read, contains a surprising amount of information for its size, and is well referenced. In addition to explaining the key points of epidemiological and clinical research designs, the book has lots of examples of good practices and bad mistakes, as well as several helpful flowcharts and illustrations. The authors write with humor (they somehow weave ancient Roman toilets and astrology into the mix) and with a great deal of authority. If you need to understand the clinical literature, this is probably the single best guide you can get.
Tom Lang, Tom Lang Communications and Training International
In this text physicians and allied health professionals will find a concise and insightful guide to the design and implementation of clinical research. Clearly written in short easy-to-digest chapters this text differs from other similar publications by providing practical clinical examples from the medical literature that highlight the concepts being discussed. Physicians, pharmacists and other allied health professions will find the insights offered by these authors to be invaluable in interpreting medical literature and established researchers will better understand how to optimize their conduct and interpretation of clinical research.
Robert Reid, Journal of Obstetrics & Gynecology Canada, 2019
